2014 Full Program - Surgical Infection Society Member Portal

Annual Meeting

Full Program

Wednesday, April 30th
7:00-9:30	President's Dinner By invitation	TBD

Thursday, May 1st
7:00-7:30	Executive Council Breakfast (By invitation)	Sienna
7:30-11:30	Executive Council Meeting (By invitation)	Sienna
6:30-7:30	Breakfast	Cobalt
7:30- 11:30	Surgical Infection Course BIOLOGY OF SEPSIS and PHARMACOLOGY Microbiology of surgical pathogens Lena Napolitano Biology and metabolism of sepsis Timoth Billiar Organ physiology and multiple organ failure/dysfunction John Marshall Antimicrobials and antibiotic pharmacodynamics Pamela Lipsett Q and A session BREAK RISK PREVENTION/PROPHYLAXIS Prevention of hospital-acquired infections E. Patchen Dellinger Clostridium difficile infections John Mazuski Q and A session SPECIFIC INFECTIONS Necrotizing soft tissue infections Brian Harbrecht Diagnosis and management of primary, secondary, and tertiary peritonitis Mark Malangoni High-risk patients: who are they and how should they be managed? Soumitra Eachempati Q and A session	Ballroom
11:30- 11:45	Nominating Committee (By invitation)	Sienna
11:45-1:00	Lunch Symposium I	Cobalt
1:00- 4:45	Plenary Symposium The Art and Science of Surgical Infections Papers 1 - 10 Moderators: William Cheadle, MD and Nicholas Namias, MD	Ballroom
	O1. Replenishing the core gut microbiome via fecal microbiota transplant (FMT) can rescue mice from advanced-stage polymicrobial sepsis. Jennifer DeFazio (Resident), presenting. University of Chicago. Discussant: John Alverdy, MD
	O2. The SIS Study To Optimize Peritoneal Infection Therapy (STOP-IT) Trial: Four Days of Antibiotics Result in Similar Outcomes Compared to Duration. Robert Sawyer, presenting. University of Virginia. Discussant: Philip Barie, MD
	O3. Expression of MiR-21 is advantageous in the Immune Response to Peritonitis. Rebecca Barnett (Resident), presenting. University of Louisville. Discussant: Michael Morowitz, MD
	O4. A prospective randomized study to assess the optimal duration of antimicrobial prophylaxis in total gastrectomy. Ryoji Fukushima, presenting. Teikyo University School of Medicine. Discussant: J Wesly Alexander, MD
	O5. Thrombin-processed Ecrg4 is chemotactic and recruits inflammatory monocytes to the injury site. Jisook Lee, presenting. University of California San Diego. Discussant: Timothy Billiar, MD
	O6. Empiric Azoles Are Not Beneficial in Surgical Patients: A Propensity-Matched Cohort Study. Christopher Guidry (Resident), presenting. University of Virginia. Discussant: Pamela Lipsett, MD
	O7. TNF-Œ±, IL-6 and IL-8 cytokines in relation to TNF-Œ±-308 G/A polymorphism in postoperative sepsis. Kavita Baghel, presenting. King George's Medical University, India. Discussant: John Marshall, MD
	O8. Obstructive sleep apnea: a risk factor for surgical site infection after colectomy. Spyridon Fortis (Resident-New Member), presenting. University of Minnesota. Discussant: E. Patch Dellinger, MD.
	O9. Are Functional Single Nucleotide Polymorphisms of Proinflammatory Cytokines Associated with the Development of Necrotizing Enterocolitis or Spontaneous Perforation in Premature Infants? Ashanti Franklin (Resident), presenting. Children’s National Medical Center. Discussant: Gary An, MD
	O10. Screening for Ventilator-Associated Pneumonia in the Surgical Intensive Care Unit: Single-Institution Analysis of 1,013 Bronchoalveolar Lavage. Fredric Pieracci, presenting. Denver Health Medical Center/University of Colorado Health Sciences Center. Discussant: Lena Napolitano, MD
4:45- 5:30	SIS Antibiotic Duration Study-Robert Sawyer, MD	Cobalt
5:30- 6:15	Surgical Infections Editorial Reception (By invitation)	TBA
6:15- 7:00	SIS Foundation Board Meeting (By invitation)	Cobalt
7:00- 8:30	Welcome Reception	Pool Deck

Friday, May 2nd
7:00-8:00	Breakfast Symposium	Cobalt
8:00- 9:45	Parallel Session I Cellular and Molecular Mechanisms (Papers 11-15) Moderators: Ori Rotstein, MD and Brian Zuckerbrain, MD	Ballroom I
	O11. Cyclic adenosine monophosphate activation of protein kinase A may play a role in the pathogenesis of necrotizing enterocolitis. Catherine Hunter , presenting. Northwestern University Discussant: Matthew Rosengart, MD
	O12. TNFR1 Level in Sepsis is Dependent on MyD88-dependent Upregulation of iNOS in Hepatocytes. Meihong Deng (Resident/New Member), presenting. UPMC. Discussant: Rachel Khadaroo, MD
	O13. Hepatic High Motility Group Box-1 (HMGB1) levels are affected by invariant Natural Killer T-cells in polymicrobial sepsis. John Young (Resident), presenting. Brown University, Rhode Island Hospital. Discussant: Ping Wang, MD
	O14. Varying Host Response in Different Low-Lethality Models of Murine Abdominal Sepsis. Lori Gentile (Resident), presenting. University of Florida College of Medicine. Discussant: Saman Arbabi, MD
	O15. Mitigation of Splenocyte Apoptosis by Th2-Polarized Invariant Natural Killer T Cells Reduces Disease Severity in Intra-abdominal Sepsis. Ram Anantha (Resident), presenting. Schulich School of Medicine and Dentistry, Western University. Discussant: Daithi Heffernan, MD
8:00-9:45	Parallel Session II Risk Factors and Surgical Infections (Papers 16-21) Moderators: E. Patch Dellinger, MD and Heather Evans, MD	Ballroom II
	O16. Can nasal methicillin-resistant Staphylococcus aureus screening be used to avoid empiric vancomycin use in intra-abdominal infection? Puja Shah (Resident), presenting. University of Virginia. Discussant: Reza Askari, MD
	O17. A randomized, prospective study of surgical site infections following vascular reconstructive surgery: untreated vs. silver-impregnated dressings. Amani Politano (Resident), presenting. University of Virginia. Discussant: Jill Cherry- Bukowiec, MD
	O18. Microbial Analysis to Predict Anastomotic Leak in Humans. Preston Luong (New Member), presenting. University of Chicago. Discussant: Brian Zuckerbraun, MD
	O19. Vancomycin-Associated Nephrotoxicity; the Obesity Factor. Stephen Davies (Resident/New Member), presenting. University of Virginia. Discussant: Heather Evans, MD
	O20. Hypoalbuminemia in Obese Surgical Patients is Disproportionately Associated With Infectious Complications. Zachary Dietch (Resident), presenting. University of Virginia. Discussant: Sheryl M. Sahr, MD
	O21. Complex pelvic surgery and additional organ resection independently increase the risk of wound infection after elective colorectal surgery: an ACS-NSQIP analysis. Mary Kwaan (New Member), presenting. University of Minnesota. Discussant: John M. Davis, MD
9:45-10:00	Break-Visit the Exhibits
10:00-11:00	William A. Altemeier Memorial Lecture. "Warping disease space to improve recovery from infections." David S Schneider, PhD Associate Professor, Microbiology and Immunology Associate Chair of the Department Stanford University School of Medicine	Ballroom
11:00-12:00	Surgical Infection Society Presidential Address "The Wheel" Nicholas Namias, MD, MBA, FACS, FCCM Professor and Chief, Division of Trauma and Acute Care Surgery Robert Zeppa Endowed Chair in Trauma Surgery Executive Vice Chairman, DeWitt Daughtry Family Department of Surgery University of Miami, Miller School of Medicine	Ballroom
12:00-1:15	Luncheon Symposium (Industry-sponsored; not part of scientific program)	Cobalt
1:30-3:15	Update Symposium I GI Fistulae, Anastamotic Leak, and Other Abdominal Catastrophes Moderators: Tina Mele, MD and Samir S. Awad, MD	Ballroom
	Topic 1: Endoscopic Approaches to Source Control: Rajeev Attam, MD Topic 2: Management of GI Fistulae, Soup to Nuts: David Efron,MD Topic 3: Microbial Pathogenesis of Anastamotic Leaks: John Alverdy, MD Topic 4: Closing the Infected Abdomen: If, When, How: Jose Diaz, MD
3:15-3:30	Break-Visit the Exhibits
3:30-5:00	Parallel Session III Basic Mechanisms of Infection (Papers 22-27) Moderators: Ori Rotstein, MD (billiar) and Daithi Heffernan, MD	Ballroom I
	O22. Oncostatin M modulates immune cell recruitment and bacterial translocation in a murine model of sepsis. Pang Young (Resident), presenting. University of Alberta. Discussant: Tina Mele, MD
	O23. Association of Inflammasomes and Caspase-1 Mediated Cardiac Dysfunction with Sepsis. Deborah Carlson, presenting. University of Florida. Discussant: Brian Eliceiri, PhD
	O24. Invariant Natural Killer T-cells modulate the Gamma-Delta-Lymphocyte response to polymicrobial sepsis. Whitney Young (Resident), presenting. Brown University, Rhode Island Hospital. Discussant: Ping Wang, MD
	O25. Glutamine Improves Innate Immunity and the Intestinal Barrier Function During Parenteral Nutrition. Rebecca Busch (Resident/New Member), presenting. University of Wisconsin Madison. Discussant: Todd Costantini, MD
	O26. Mesenchymal Stem Cells Reverse Chronic Stress Induced Bone Marrow Dysfunction Following Traumatic Injury. Amy Gore (Resident), presenting. NJMS-Rutgers. Discussant: William Cheadle, MD
	O27. Wound Infection after Attenuating a Key Inflammatory Signaling Pathway. Saman Arbabi, presenting. University of Washington. Discussant: Olga Zaborina, PhD
3:30-5:00	Parallel Session IV Hospital Acquired and Skin/Soft Tissue Infections (Papers 28-33) Moderators: John Mazuski, MD, PhD and Addison May, MD	Ballroom II
	O28. Reduction of infectious complications following trauma laparotomy through use of a perioperative antibiotic protocol. William Symons (New Member), presenting. Washington University. Discussant: Jeffery Claridge, MD
	O29. Sustainability of a Hospital-Acquired Pressure Ulcer Prevention Bundle In Surgical Patients. Sylvia Martinez, presenting. Baylor College of Medicine. Discussant: Sandy Swoboda RN, MSN
	O30. Ventilator-associated Events: Correlation with Ventilator-associated Pneumonia? Arek Wiktor (Resident/New Member), presenting. University of Michigan Health System. Discussant: Fred Pierraci, MD
	O31. Health-Related Quality of Life Among Necrotizing Soft Tissue Infection Survivors and Clinical Predictors of Poor Outcome. Timo Hakkarainen (Resident), presenting. University of Washington. Discussant: Jeffrey G. Chipman, MD
	O32. A Surgeon-Directed Peripherally Inserted Central Catheter Team Utilizing a Novel Screening Protocol to Decrease Infectious Complications and Associated Cost. Vihas Patel (Resident), presenting. Brigham and Women. Discussant: Laura Moore, MD
	O33. Predictors of Mortality Among Intravenous Drug Users with Staphylococcus aureus Bacteremia. Ram Anantha (Resident), presenting. Schulich School of Medicine and Dentistry, Western University. Discussant: Colin Braithwaite, MD
5:00-6:00	Annual Business Meeting(Members only)	Ballroom II
6:00-7:00	Committee Meetings (Attendance mandatory for committee members)	Cobalt

Saturday, May 3rd
7:00-8:00	Executive Council Meeting (By invitation)	Sienna
7:00-8:00	Breakfast	Cobalt
8:00-9:00	Update Symposium II Pro-Con Debates Moderators: Matthew R. Rosengart *The Double X Chromosome: Does Gender Really Matter in Human Disease?* Speakers: PRO: Jason Sperry, MD CON: Addison May, MD *Is Zero Achievable in CLABSI, CAUTI, and VAP?* Speakers: PRO: Madhuri Sopirala, MD-University of Cincinnati CON: Zero Dark Dirty!-Robert Sawyer, MD-University of Virginia	Ballroom
9:00-10:00	Update Symposium III Advanced Platform Technologies: An Update Moderator: John Alverdy Topic 1: A Metagenomic Approach to Understand Surgical Infection-The Role of Next Generation Technology-Jack Gilbert, PhD-Argonne National Laboratory Topic 2: Computational Needs and Approaches to Manage Metagenomic Data-Scott Christley, PhD Topic 3: Statistical Analysis of Megadatasets-Managing Terabytes of Data? Paul Bankey, MD, PhD	Ballroom
10:00-10:15	Fellowship Award Recipient Presentations Moderators: Philip S. Barie, MD, MBA and Evan Nadler, MD SIS Foundation Resident Fellowship 2014 SIS Foundation Junior Faculty Fellowship 2014	Ballroom
10:15-10:30	Break-Visit the Exhibits
10:30-12:00	Parallel Session V Proteins, Genes, and Pathogens (Papers 34-38) Moderators: John Marshall, MD and Rachel Khadaroo, MD, PhD	Ballroom I
	O34. The Enteric Nervous System (ENS) Neuropeptide, Bombesin (BBS), Maintains Goblet Cell Function During Parenteral Nutrition (PN). Aaron Heneghan (New Member), presenting. University of Wisconsin Madison. Discussant: Jared Huston, MD
	O35. Computational prediction of a novel transcriptional regulation for the PqsH encoding gene in Pseudomonas aeurginosa. Scott Christley, presenting. University of Chicago. Discussant: Kaysie Banton,MD
	O36. The Genomic Expression of Aged Murine Hematopoietic Stem Cells after Polytrauma Indicates a Failure to Support Development of Innate Immunity. Philip Efron, presenting. University of Florida. Discussant: Joseph Minei, MD
	O37. Ursodeoxycholic acid as a mediator of intestinal epithelial cell restitution. Stephanie Papillon (Resident), presenting. Children's Hospital Los Angeles. Discussant: John Alverdy, MD
	O38. NEC as an infectious disease: Identifying strains of opportunistic pathogens. Debi Thomas, presenting. Children's Hospital of Los Angeles. Discussant: Evan Nadler, MD
10:30-12:00	Parallel Session VI Clinical Issues in Surgical Infection (Papers 39-44) Moderators: Lilian Kao, MD and Jeffery Chipman, MD	Ballroom II
	O39. A Systematic Approach to Preventing Sharps Injuries in the Operative Care Line at an Urban Tertiary Care Center. Sylvia Martinez , presenting. Baylor College of Medicine. Discussant: Peter A Burke, MD
	O40. Acute kidney injury (AKI) causes persistent dysregulation of the leukocyte transcriptome. Benjamin Szpila (Resident), presenting. University of Florida College of Medicine Discussant: David Efron, MD
	O41. External Validation of the Ventral Hernia Risk Score for Predicting Surgical Site Infections. Mike Liang (New Member), presenting. University of Texas Health Sciences Center. Discussant: Donald Fry, MD
	O42. Use of Computed Tomography to Diagnose Aspiration in Trauma Patients. Vanessa Fawcett, presenting. University of Washington. Discussant: Lewis Kaplan, MD
	O43. Predictors of Monomicrobial Necrotizing Fasciitis. Rhett Willis (Resident/New Member), presenting. University of Virginia. Discussant: Addison May, MD
	O44. Transforming growth factor beta induced epithelial-mesenchymal transition leads to persistent intestinal fistulae. Xiuwen, presenting. Jinling Hospital, China. Discussant: Catherine Hunter, MD
12:00-1:15	Luncheon Symposium (Industry-sponsored; not part of scientific program)	Cobalt
1:30-3:00	Parallel Session VII Pathophysiologic Mechanisms of Infection (Papers 45-49) Moderators: Marc Jeschke, MD, PhD and Catherine Hunter, MD	Ballroom I
	O45. Genomic and Proteomic Survival Biomarker Profiles in Severely Burned Children. Celeste Finnerty (Resident), presenting. University of Texas Medical Branch / Shriners Hospitals for Children. Discussant: Marc Jeschke, MD
	O46. Intestinal bile acids differentially control intestinal cell proliferation. Avafia Dossa (Resident), presenting. Children's Hospital Los Angeles. Discussant: Ziad Sifri, MD
	O47. The gut during prolonged critical illness harbors low membership pathogen communities that are less virulent as a group than individually. Olga Zaborina, presenting. University of Chicago. Discussant: Mary Kwaan, MD
	O48. Muscle Injury and Ischemia Contribute to the Pathogenesis of A. baumannii Infection. Irma Fleming (Resident), presenting. University of Chicago. Discussant: Duane Hospenthal, MD
	O49. Differential Immune and Hormonal Expression in Cardiac Versus Hepatic Blood after Burn Injury in Rodents. Marc Jeschke (Resident), presenting. Sunnybrook Health Sciences Centre. Discussant: Tina Palmieri, MD
1:30-3:00	Parallel Session VIII The Surgical Infection Society Supreme Court (Papers 50-54) Moderators: Pamela Lipsett, MD, MHE, and Nicholas Namias, MD, MBA, John Alverdy, MD, Robert Sawyer and Patch Dellinger	Ballroom II
	O50. A Reappraisal of MRSA VAP in the Surgical ICU: Not Just a Late Infection Any More.. Jacquelyn Glenn, presenting. Denver Health Medical Center.
	O51. Environmental contact versus patient contact in the ICU: what do we touch? Sandy Swoboda, presenting. Johns Hopkins.
	O52. Early appropriate empiric antimicrobial prescribing in septic patients presenting to the emergency department does not lead to decreased mortality. James Gilmore (Resident), presenting. Brigham and Women.
	O53. CAUTIs and CLABSIs: Do physicians REALLY know what they are? Therese Duane, presenting. Virginia Commonwealth University Medical Center.
	O54. A Comparison of ICU infections in a United States Trauma Center and a Teaching Hospital in Ho Chi Minh City, Vietnam. Daithi Heffernan, presenting. Brown University.
4:00-5:20	Poster Session (Posters 1-52) Basic and Clinical Studies in Surgical Infection Moderators: Group A: (P1-P8) Olga Zaborina, PhD and Marc Jeschke, MD Group B: (P9-P17) Brian Elicieri, PhD and Celeste Finnerty, PhD Group C: (P18-P27) Jeffery Tessier, MD and Therese Duane, MD Group D: (P28-P33) Kaysie Banton, MD and David Blake, MD Group E: (P34-P43) Reza Askari, MD and Howard Belzberg, MD Group F: (P44-P52) Christine S. Cocanour, MD and Samir Awad, MD	Ballroom Foyer
7:00-8:00	New Member Reception	Ballroom Foyer
8:00-10:00	Awards Banquet	Ballroom
10:00	ADJOURNMENT

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Prevention and Education

Full Program

Wednesday, April 30th

Thursday, May 1st

Friday, May 2nd

Saturday, May 3rd